Samuel O. Oyola

Samuel O. Oyola

Senior Scientist: Molecular Biologist and Head of Genomics

Samuel Oyola is ILRI’s Specialist Scientist in Genomics and Molecular Biology. He holds a PhD in Molecular and Cellular Biology from the University of Cambridge. Before joining ILRI, he studied functional genomics of Leishmaniasis and host-parasite interaction as a postdoctoral fellow at the University of York. He then took a Scientist position at the Wellcome Trust Sanger Institute, Cambridge UK, where he worked on malaria; developing and applying high throughput genomic technologies to study natural genetic variations in malaria parasite populations. He developed novel molecular tools that enable application and translation of genomic technologies into basic healthcare and public health applications. At ILRI, Samuel is using his experience and expertise in modern genomics, biotechnology and molecular biology to study several aspects of animal and human health. Under epidemiology, Samuel is using modern genomic and bioinformatic tools to study epidemiology of rift valley fever virus (RVF), African swine fever virus (ASFV), Newcastle disease virus (NDV) and Peste des petits ruminants virus (PPRV), SARS-CoV-2 (COVID-19) and Climate-aggravated infectious diseases such as those caused by Arboviruses. Under vaccine development, Samuel is employing his immunogenetics expertise to develop anti-east coast fever vaccine by profiling antibody immune (B-cell receptor repertoire) responses to candidate vaccine immunizations.  Samuel is also actively involved in developing Genomic Surveillance capacity in Africa.

My Projects

BUILD

Boosting Uganda’s investment in livestock development

Co-infection

Co-infection with Rift Valley fever virus, Brucella spp. and Coxiella burnetii in humans and animals in Kenya: Disease burden and ecological factors

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My Publications

Detection and prevalence of a novel Bandavirus related to Guertu virus in Amblyomma gemma ticks and human populations in Isiolo County, Kenya

  • Koka, H.
  • Langat, S.
  • Oyola, Samuel O.
  • Cherop, F.
  • Rotich, G.
  • Mutisya, J.
  • Ofula, V.
  • Limbaso, K.
  • Ongus, J.R.
  • Lutomiah, J.
  • Sang, R.

Complete genome sequencing and comparative phylogenomics of nine African swine fever virus (ASFV) isolates of the virulent East African p72 genotype IX without viral sequence enrichment

  • Domelevo Entfellner, Jean-Baka
  • Okoth, Edward A.
  • Onzere, C.K.
  • Upton, C.
  • Njau, E.P.
  • Höper, D.
  • Henson, Sonal P.
  • Oyola, Samuel O.
  • Bochere, Edwina
  • Machuka, Eunice M.
  • Bishop, Richard P.

Genome characterization of Rift Valley fever virus isolated from cattle, goats and sheep during interepidemic periods in Kenya

  • Onwong'a, A.A.
  • Oyola, Samuel O.
  • Juma, John
  • Konongoi, S.
  • Nyamota, Richard
  • Mwangi, Reuben
  • Muli, Collins
  • Dobi, Paul
  • Bett, Bernard K.
  • Ongus, J.R.

Altitude-dependent agro-ecologies impact the microbiome diversity of scavenging indigenous chicken in Ethiopia

  • Glendinning, L.
  • Jia, X.
  • Kedebe, Adebabay
  • Oyola, Samuel O.
  • Park, J.-E.
  • Park, W.
  • Assiri, A.
  • Holm, J.B.
  • Kristiansen, K.
  • Han Jianlin
  • Hanotte, Olivier H.

Genomic epidemiology of Rift Valley fever virus involved in the 2018 and 2022 outbreaks in livestock in Rwanda

  • Nsengimana, I.
  • Juma, John
  • Roesel, Kristina
  • Gasana, M.N.
  • Ndayisenga, F.
  • Muvunyi, C.M.
  • Hakizimana, E.
  • Hakizimana, J.N.
  • Eastwood, G.
  • Chengula, A.A.
  • Bett, Bernard K.
  • Kasanga, C.J.
  • Oyola, Samuel O.

Widening geographic range of Rift Valley fever disease clusters associated with climate change in East Africa

  • Situma, S.
  • Nyakarahuka, L.
  • Omondi, E.
  • Mureithi, M.
  • Mweu, M.M.
  • Muturi, M.
  • Mwatondo, A.
  • Dawa, J.
  • Konongoi, L.
  • Khamadi, S.
  • Clancey, E.
  • Lofgren, E.
  • Osoro, E.
  • Ngere, I.
  • Breiman, R.F.
  • Bakamutumaho, B.
  • Muruta, A.
  • Gachohi, J.
  • Oyola, Samuel O.
  • Njenga, M.K.
  • Singh, D.
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